🧬PDRN (Salmon DNA)
The foundation of the PDRN Collection
A clinically inspired polynucleotide selected to support hydration and healthier looking skin.

20% OffPDRN
Pairs well with
PDRN Peptide Cream
$63.20 AUD
Presale. Ships September 20
An everyday hydration serum that supports smoother, healthier looking skin.
(3 Reviews)via Judge.mePDRN Skincare
The PURESKIN PDRN Peptide Serum combines clinically inspired PDRN Technology with a precision dual peptide complex, six forms of hyaluronic acid and barrier supporting ingredients to deliver lasting hydration and improve overall skin comfort.
$71.20 AUD$89.00 AUD
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PDRN Technology
Clinically inspired Salmon DNA supporting hydration and healthier looking skin.
Precision Peptide Pair
Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 work together to support smoother, firmer looking skin.
6 Form Hyaluronic Acid Complex
Six complementary forms of hyaluronic acid, with Hydrolyzed Collagen, deliver immediate and lasting hydration.
Barrier Support Complex
Ceramide NP, Beta-Glucan, Panthenol and Ectoin help strengthen the skin barrier and improve comfort.
Every PURESKIN formula is purposefully developed around clinically inspired actives, barrier first science and ingredient synergy, because healthier looking skin starts with better formulation.
The foundation of the PDRN Collection
A clinically inspired polynucleotide selected to support hydration and healthier looking skin.

Advanced peptide technology
A carefully selected blend of biomimetic peptides that support smoother, firmer looking skin.

Barrier Lipid
Helps replenish essential barrier lipids and strengthen the skin's moisture barrier.

Environmental Defence
An advanced extremolyte that helps defend against environmental stress while maintaining hydration.

Layered Hydration
Multiple molecular weights deliver hydration throughout the skin for immediate and lasting moisture.

Barrier Support
A soothing polysaccharide that helps reinforce the skin barrier while improving moisture retention.

Botanical Recovery
Rich in calming compounds that help comfort stressed skin and support a healthier looking complexion.

Skin Conditioning
A well studied vitamin B3 derivative that supports an even, refined and healthier looking complexion.

PDRN Technology
Peptide Complex
Multi Layer Hydration
Barrier Recovery
Every formula is designed to complement the next, creating a complete routine focused on hydration, recovery and barrier support.
Simple. Powerful.
Lara
Verified12/08/2026 · Australia
I was lucky enough to receive early access on these products and they did not disappoint! The serum is my favourite & my skin feels healthier after only 1 week.
Samantha
Verified10/08/2026 · Australia
The serum absorbs so nicely into the skin without feeling stick and heavy. My skin looks noticeably clearer after only a week.
Maria
Verified07/08/2026 · Australia
I ordered the serum to try first, but now I want to try everything!
Clinically inspired PDRN serum
PDRN is the hero ingredient, but exceptional skincare relies on ingredient synergy. That's why we've paired high purity PDRN with barrier supporting lipids, advanced hydration technologies and clinically inspired recovery actives, creating a formula designed to perform as a complete skin recovery system.
PDRN
The Hero Technology
High purity salmon DNA fragments: the regenerative core of the formula.
Hydration
Multi Level Moisture
Multi weight hyaluronic acid with ectoin for hydration through every layer.
Barrier
Skin Barrier Support
Ceramide NP, beta-glucan and panthenol to reinforce the barrier.
Skin Conditioning
Daily Skin Optimisation
Niacinamide and recovery actives for a smoother, more even looking finish.
It's not just salmon DNA. It's PDRN delivered alongside the barrier lipids, hydration architecture and conditioning actives that let it perform: a complete, clinically inspired recovery system.
Formula comparison
PDRN is only the beginning.
PURESKIN combines PDRN with peptides, advanced hydration technology and barrier supporting actives to create a more comprehensive approach to skin hydration, resilience and visibly healthier looking skin.


PURESKIN PDRN Peptide Serum
PDRN + Peptides + Hydration + Barrier Support

Typical PDRN Serum
PDRN alone
PURESKIN PDRN Serum was formulated to go beyond a single hero ingredient.
At its core is Salmon DNA (PDRN), complemented by a multi peptide complex and a sophisticated hydration and barrier support system.
Six forms of hyaluronic acid provide multi level hydration, while Ceramide NP, Ectoin and Beta-Glucan support the skin barrier and help maintain skin comfort.
Niacinamide and Panthenol further support hydration and skin conditioning, while Hydrolyzed Collagen complements the formula for smoother, plumper looking skin.
The result is a multi active PDRN serum designed around PDRN + Peptides + Hydration + Barrier Support, rather than PDRN alone.
PDRN is the hero. The formula around it makes the difference.
The PURESKIN PDRN Peptide Serum is built around clinically inspired PDRN Technology, advanced peptide science and multi layer hydration, where every ingredient is selected to work in synergy, not isolation.
PDRN (Salmon DNA): clinically inspired polynucleotide technology that forms the foundation of the formula.
Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 work together to support smoother, firmer and healthier looking skin.
Six complementary forms of hyaluronic acid work alongside Hydrolyzed Glycosaminoglycans and Hydrolyzed Collagen for immediate and lasting hydration.
Ceramide NP, Beta-Glucan, Panthenol and Ectoin help reinforce the skin barrier and improve lasting comfort.
Beyond hydration and peptides, the formula is enriched with Niacinamide, Centella Asiatica, Oat Extract, Gentiana Scabra Root Extract and Adenosine to help support a smoother, healthier looking complexion.
PDRN SALMON DNA
Unlike formulas that rely on a single hero ingredient, the PURESKIN PDRN Peptide Serum combines clinically inspired PDRN Technology with advanced peptides, multi layer hydration and barrier supporting ingredients to deliver a complete daily treatment.
Hero Technology
Clinically inspired PDRN (Salmon DNA) forms the foundation of the formula, supporting hydration and promoting healthier looking skin.
Precision Peptide Pair
Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 work together to support smoother, firmer and healthier looking skin.
6 Form Hyaluronic Acid Complex
Six complementary forms of hyaluronic acid work alongside Hydrolyzed Glycosaminoglycans and Hydrolyzed Collagen to provide immediate hydration, improved moisture retention and a smoother, plumper looking complexion.
Barrier Recovery Complex
Ceramide NP, Beta-Glucan, Panthenol and Ectoin help replenish moisture, strengthen the skin barrier and improve long term skin comfort.
Your routine
Use morning and night as part of your PDRN ritual. Apply to clean skin and follow with your moisturiser.
☀️Morning
Protect & Hydrate
🌙Evening
Repair & Recover
How it fits together
Cleanse
Daily
Serum
Daily
Cream
Daily
Mask
1–2x weekly
The full routine
Four clinically inspired formulas designed to work together as one complete recovery system.

🫧 Cleanse
PDRN Hydrating Cleanser

🧬 Treat
PDRN Peptide Serum

🛡️ Moisturise
PDRN Peptide Cream

💧 Mask
PDRN Hydrogel Mask (4-pack)
THE PDRN COLLECTION
Discover the complete PURESKIN PDRN Collection. Four clinically inspired formulas developed to cleanse, hydrate, support the skin barrier and promote healthier looking skin.
Shop The PDRN CollectionSecure checkout· Free shipping $120+
Complete the ritual
Free shipping on orders over $120