🧬PDRN (Salmon DNA)
The foundation of the PDRN Collection
A clinically inspired polynucleotide selected to support hydration and healthier looking skin.
🇦🇺 Australian Owned•🚚 Free Shipping On Orders Over $120 AU Only•🌍 We Ship Worldwide•🎁 Free Gift On Orders Over $100•📦 Same Day Dispatch Before 12pm•🐰 Cruelty Free•🌸 Fragrance Free•🇦🇺 Australian Owned•🚚 Free Shipping On Orders Over $120 AU Only•🌍 We Ship Worldwide•🎁 Free Gift On Orders Over $100•📦 Same Day Dispatch Before 12pm•🐰 Cruelty Free•🌸 Fragrance Free•
20% OffPDRNPDRN Peptide Serum in action
A lightweight, fast absorbing treatment that supports skin recovery while delivering long lasting hydration. PDRN (Salmon DNA), copper peptides, multi-weight hyaluronic acid, Beta-Glucan and Ceramide NP work together to help strengthen the skin barrier and improve the appearance of dull, tired skin.
Free Shipping to Australia
On orders over $120 AUD
US & UAE: estimated delivery 5–10 business days
International shipping calculated at checkout
Pairs well with
PDRN Peptide Cream
$63.20 AUD
PDRN Peptide Serum
An everyday hydration serum that supports smoother, healthier looking skin.
(11 Reviews)via Judge.mePDRN Skincare
The PURESKIN PDRN Peptide Serum combines clinically inspired PDRN Technology with a precision dual peptide complex, six forms of hyaluronic acid and barrier supporting ingredients to deliver lasting hydration and improve overall skin comfort.
$71.20 AUD$89.00 AUD
Free shipping on orders over $120 · Same day dispatch before 12pm
Customers who bought this also bought
- PDRN Peptide Cream+ $63.20 AUD
- PDRN Hydrogel Mask (4-pack)+ $55.20 AUD
🧬PDRN Technology
🧪Dual Peptide Complex
💧6 Forms of Hyaluronic Acid
🛡️Barrier Support Complex
Secure checkout · Visa · Mastercard · Amex · Apple Pay · Afterpay
Four Advanced Skin Technologies
PDRN Technology
Clinically inspired Salmon DNA supporting hydration and healthier looking skin.
Precision Peptide Pair
Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 work together to support smoother, firmer looking skin.
6 Form Hyaluronic Acid Complex
Six complementary forms of hyaluronic acid, with Hydrolyzed Collagen, deliver immediate and lasting hydration.
Barrier Support Complex
Ceramide NP, Beta-Glucan, Panthenol and Ectoin help strengthen the skin barrier and improve comfort.
Clinical skincare, elevated.
Every PURESKIN formula is purposefully developed around clinically inspired actives, barrier first science and ingredient synergy, because healthier looking skin starts with better formulation.
Clinically inspired FormulasPurposefully FormulatedPerformance Driven Ingredients
🧬Precision Peptides
Advanced peptide technology
A carefully selected blend of biomimetic peptides that support smoother, firmer looking skin.
🛡️Ceramide NP
Barrier Lipid
Helps replenish essential barrier lipids and strengthen the skin's moisture barrier.
🌿Ectoin
Environmental Defence
An advanced extremolyte that helps defend against environmental stress while maintaining hydration.
💧Multi Weight Hyaluronic Acid
Layered Hydration
Multiple molecular weights deliver hydration throughout the skin for immediate and lasting moisture.
🛡️Beta-Glucan
Barrier Support
A soothing polysaccharide that helps reinforce the skin barrier while improving moisture retention.
🌱Centella Asiatica
Botanical Recovery
Rich in calming compounds that help comfort stressed skin and support a healthier looking complexion.
✨Niacinamide
Skin Conditioning
A well studied vitamin B3 derivative that supports an even, refined and healthier looking complexion.
Why This Formula Works
🧬
PDRN Technology
🧬
Peptide Complex
💧
Multi Layer Hydration
🛡️
Barrier Recovery
Clinically inspired.
Every formula is designed to complement the next, creating a complete routine focused on hydration, recovery and barrier support.
Simple. Powerful.
11 Reviews
Verified customersLara Clarke
Verified13/10/2026 · Melbourne, Victoria, Australia
Such an amazing serum! I absolutely love how lightweight and hydrating it feels on my skin. It absorbs so nicely without leaving any sticky or oily residue and makes my skin feel instantly soft, smooth and refreshed. I’ve noticed my skin looking more radiant, plump and healthy since adding this into my skincare routine. It’s super gentle, sits beautifully under moisturiser and makeup, and gives my skin that extra boost of hydration it needs. Definitely a product I’ll continue using and would highly recommend!
Layla
Verified12/10/2026 · Melbourne, Victoria, Australia
I love this serum, my skin feels so soft and plump! recommend for anyone buying💕
Olivia
Verified12/10/2026 · Melbourne, Victoria, Australia
The best PDRN serum I’ve tried hands down!
Maya
Verified12/10/2026 · Melbourne, Victoria, Australia
Makes my skin glow, really happy with it after 2 weeks
Julia
Verified12/10/2026 · Melbourne, Victoria, Australia
Omg this is my new fave serum! It’s so light but makes my skin look so glowy!
Maria Berak
Verified06/10/2026 · Melbourne, Victoria, Australia
Hydrating, brightening and so light on the skin. Absorbs extremely well. Skin feels firmer and its only day 3. Loving it so far
Mikayla L
Verified06/10/2026 · Melbourne, Victoria, Australia
I love this serum! I’ve been using it for a couple of weeks and my skin has this amazing glow. I love that they include barrier supporting ingredients too. I almost finished the whole bottle already!
Jessica
Verified28/10/2026 · Melbourne, Victoria, Australia
Absolutely love this serum! It feels so lightweight and absorbs beautifully without leaving my skin feeling sticky or greasy. My skin feels so much more hydrated, soft and smooth since I started using it. It also gives my skin such a nice healthy glow! Definitely become a staple in my skincare routine, I’m on to my second bottle already!
Lara
Verified12/08/2026 · Australia
I was lucky enough to receive early access on these products and they did not disappoint! The serum is my favourite & my skin feels healthier after only 1 week.
Samantha
Verified10/08/2026 · Australia
The serum absorbs so nicely into the skin without feeling stick and heavy. My skin looks noticeably clearer after only a week.
Maria
Verified07/08/2026 · Australia
I ordered the serum to try first, but now I want to try everything!
Loved your order?
Click below and leave us a review — it means the world to a small brand like ours.
Leave a reviewClinically inspired PDRN serum
Salmon DNA skincare is trending right now.
Our version is giving K-beauty x Pharmaceutical.
PDRN is the hero ingredient, but exceptional skincare relies on ingredient synergy. That's why we've paired high purity PDRN with barrier supporting lipids, advanced hydration technologies and clinically inspired recovery actives, creating a formula designed to perform as a complete skin recovery system.
🧬
PDRN
The Hero Technology
High purity salmon DNA fragments: the regenerative core of the formula.
💧
Hydration
Multi Level Moisture
Multi weight hyaluronic acid with ectoin for hydration through every layer.
🛡️
Barrier
Skin Barrier Support
Ceramide NP, beta-glucan and panthenol to reinforce the barrier.
✨
Skin Conditioning
Daily Skin Optimisation
Niacinamide and recovery actives for a smoother, more even looking finish.
PDRN Works Best In Good Company.
🧬PDRN
🛡️Barrier Lipids
💧Multi Weight Hyaluronic Acid
🌾Beta-Glucan
🛡️Ectoin
✨Niacinamide
🌿Panthenol
It's not just salmon DNA. It's PDRN delivered alongside the barrier lipids, hydration architecture and conditioning actives that let it perform: a complete, clinically inspired recovery system.
Formula comparison
Not All PDRN Serums Are Created Equal.
PDRN is only the beginning.
PURESKIN combines PDRN with peptides, advanced hydration technology and barrier supporting actives to create a more comprehensive approach to skin hydration, resilience and visibly healthier looking skin.
PURESKIN PDRN Peptide Serum
PDRN + Peptides + Hydration + Barrier Support
Typical PDRN Serum
PDRN alone
FormulationPURESKIN PDRN SerumTypical PDRN Serum
PDRN / Sodium DNAIncluded
Multi Peptide ComplexIncludedLimited / Not standard
6 Form Hyaluronic Acid ComplexIncluded
Ceramide NP Barrier SupportIncluded
Ectoin + Beta-GlucanIncluded
Niacinamide + PanthenolIncluded
Hydrolyzed CollagenIncluded
Multi Level Hydration SystemIncluded
Barrier Supporting ActivesIncludedLimited
More Than PDRN.
PURESKIN PDRN Serum was formulated to go beyond a single hero ingredient.
At its core is Salmon DNA (PDRN), complemented by a multi peptide complex and a sophisticated hydration and barrier support system.
Six forms of hyaluronic acid provide multi level hydration, while Ceramide NP, Ectoin and Beta-Glucan support the skin barrier and help maintain skin comfort.
Niacinamide and Panthenol further support hydration and skin conditioning, while Hydrolyzed Collagen complements the formula for smoother, plumper looking skin.
The result is a multi active PDRN serum designed around PDRN + Peptides + Hydration + Barrier Support, rather than PDRN alone.
PDRN is the hero. The formula around it makes the difference.
Every Ingredient. One Purpose.
The PURESKIN PDRN Peptide Serum is built around clinically inspired PDRN Technology, advanced peptide science and multi layer hydration, where every ingredient is selected to work in synergy, not isolation.
🧬 PDRN Technology🧪 Peptide Powered💧 6 Form Hydration
🧬Hero Technology
PDRN (Salmon DNA): clinically inspired polynucleotide technology that forms the foundation of the formula.
🧪Precision Peptide Pair
Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 work together to support smoother, firmer and healthier looking skin.
💧6 Form Hyaluronic Acid Complex
Six complementary forms of hyaluronic acid work alongside Hydrolyzed Glycosaminoglycans and Hydrolyzed Collagen for immediate and lasting hydration.
🛡️Barrier Recovery
Ceramide NP, Beta-Glucan, Panthenol and Ectoin help reinforce the skin barrier and improve lasting comfort.
Supporting Skin Condition
Beyond hydration and peptides, the formula is enriched with Niacinamide, Centella Asiatica, Oat Extract, Gentiana Scabra Root Extract and Adenosine to help support a smoother, healthier looking complexion.
Free shipping over $120Same day dispatch before 12pmAustralian ownedClinically inspired formulasFree shipping over $120Same day dispatch before 12pmAustralian ownedClinically inspired formulasFree shipping over $120Same day dispatch before 12pmAustralian ownedClinically inspired formulasFree shipping over $120Same day dispatch before 12pmAustralian ownedClinically inspired formulasFree shipping over $120Same day dispatch before 12pmAustralian ownedClinically inspired formulasFree shipping over $120Same day dispatch before 12pmAustralian ownedClinically inspired formulasFree shipping over $120Same day dispatch before 12pmAustralian ownedClinically inspired formulasFree shipping over $120Same day dispatch before 12pmAustralian ownedClinically inspired formulas
PDRN SALMON DNA
More Than A PDRN Serum. Built Around Ingredient Synergy.
Unlike formulas that rely on a single hero ingredient, the PURESKIN PDRN Peptide Serum combines clinically inspired PDRN Technology with advanced peptides, multi layer hydration and barrier supporting ingredients to deliver a complete daily treatment.
🧬
Hero Technology
Clinically inspired PDRN (Salmon DNA) forms the foundation of the formula, supporting hydration and promoting healthier looking skin.
🧪
Precision Peptide Pair
Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 work together to support smoother, firmer and healthier looking skin.
💧
6 Form Hyaluronic Acid Complex
Six complementary forms of hyaluronic acid work alongside Hydrolyzed Glycosaminoglycans and Hydrolyzed Collagen to provide immediate hydration, improved moisture retention and a smoother, plumper looking complexion.
🛡️
Barrier Recovery Complex
Ceramide NP, Beta-Glucan, Panthenol and Ectoin help replenish moisture, strengthen the skin barrier and improve long term skin comfort.
Your routine
Your PDRN Recovery Routine
Use morning and night as part of your PDRN ritual. Apply to clean skin and follow with your moisturiser.
☀️Morning
Protect & Hydrate
🌙Evening
Repair & Recover
How it fits together
🫧
Cleanse
Daily
🧬
Serum
Daily
🛡️
Cream
Daily
🩷
Mask
1–2x weekly
The full routine
The Complete PDRN Collection
Four clinically inspired formulas designed to work together as one complete recovery system.
- ✓PDRN Hydrating Cleanser
- ✓PDRN Peptide Serum
- ✓PDRN Peptide Cream
- ✓PDRN Hydrogel Mask (4-Pack)
$209.00 AUD$296.00 AUDSave $87.00 AUD30% Off
🫧 Cleanse
PDRN Hydrating Cleanser
🧬 Treat
PDRN Peptide Serum
🛡️ Moisturise
PDRN Peptide Cream
💧 Mask
PDRN Hydrogel Mask (4-pack)
THE PDRN COLLECTION
Healthy Skin Starts With The Right Foundation.
Discover the complete PURESKIN PDRN Collection. Four clinically inspired formulas developed to cleanse, hydrate, support the skin barrier and promote healthier looking skin.
Shop The PDRN CollectionSecure checkout· Free shipping $120+
Complete the ritual
More from the PDRN range
Free shipping on orders over $120