🧬PDRN (Salmon DNA)
The foundation of the PDRN Collection
A clinically inspired polynucleotide selected to support hydration and healthier looking skin.

20% OffPDRN
Pairs well with
PDRN Peptide Serum
$71.20 AUD
Presale. Ships September 20
A barrier replenishing daily moisturiser developed for lasting hydration and healthier looking skin.
PDRN Skincare
More than a moisturiser. The PURESKIN PDRN Peptide Cream combines clinically inspired PDRN Technology, Premium EGF Peptide and a Barrier Recovery Complex to help replenish moisture, strengthen the skin barrier and deliver lasting comfort throughout the day.
$63.20 AUD$79.00 AUD
Free shipping on orders over $120 · Same day dispatch before 12pm
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PDRN Technology
Clinically inspired Salmon DNA supporting hydration and healthier looking skin.
Premium EGF Peptide
Oligopeptide-1 helps support smoother, firmer and healthier looking skin.
Barrier Recovery Complex
Ceramide NP, Beta-Glucan and Panthenol reinforce the skin's moisture barrier.
Advanced Hydration
Ectoin and Sodium Hyaluronate provide lasting hydration throughout the day.
Every PURESKIN formula is purposefully developed around clinically inspired actives, barrier first science and ingredient synergy, because healthier looking skin starts with better formulation.
The foundation of the PDRN Collection
A clinically inspired polynucleotide selected to support hydration and healthier looking skin.

Advanced peptide technology
A carefully selected blend of biomimetic peptides that support smoother, firmer looking skin.

Barrier Lipid
Helps replenish essential barrier lipids and strengthen the skin's moisture barrier.

Environmental Defence
An advanced extremolyte that helps defend against environmental stress while maintaining hydration.

Layered Hydration
Multiple molecular weights deliver hydration throughout the skin for immediate and lasting moisture.

Barrier Support
A soothing polysaccharide that helps reinforce the skin barrier while improving moisture retention.

Botanical Recovery
Rich in calming compounds that help comfort stressed skin and support a healthier looking complexion.

Skin Conditioning
A well studied vitamin B3 derivative that supports an even, refined and healthier looking complexion.

PDRN Technology
Premium EGF Peptide
Barrier Recovery Complex
Advanced Hydration
Every formula is designed to complement the next, creating a complete routine focused on hydration, recovery and barrier support.
Simple. Powerful.
Formula Architecture
The PURESKIN PDRN Peptide Cream is more than a daily moisturiser. It's a clinically inspired barrier recovery treatment designed to deeply hydrate, replenish essential skin lipids and support healthier looking skin. Powered by PDRN (Salmon DNA) and an advanced blend of barrier supporting ingredients, biomimetic peptides and lasting hydrators, every ingredient has been selected to strengthen the skin barrier, improve comfort and support long term skin resilience.
PDRN
The Hero Technology
At the heart of the formula is PDRN (Salmon DNA), a clinically inspired polynucleotide selected to support skin hydration, visible recovery and a healthier looking complexion.
Hero Ingredient
Barrier
Barrier Recovery Complex
A healthy skin barrier is the foundation of healthy skin. Ceramide NP, Panthenol and Beta-Glucan work together to replenish barrier lipids, reduce moisture loss and improve skin resilience.
Hero Ingredients
Peptide Support
Biomimetic Skin Conditioning
Unlike many everyday moisturisers, this formula features Oligopeptide-1 (EGF), a premium biomimetic peptide selected to support smoother, healthier looking skin. Combined with PDRN, it helps create a more advanced skin conditioning system than hydration alone.
Hero Ingredient
Nourishment
Lasting Comfort
A blend of advanced emollients and skin conditioning ingredients helps lock in hydration while improving softness, comfort and overall skin resilience throughout the day.
Hero Ingredients
Many moisturisers focus on hydration alone. The PURESKIN PDRN Peptide Cream combines four complementary technologies in one formula: PDRN Technology, a Barrier Recovery Complex, premium Peptide Support and lasting Nourishment. Each technology has been carefully selected to complement the next, creating a moisturiser that supports hydration, barrier function and overall skin health, not just temporary moisture.
Why PURESKIN took a different approach. Many barrier creams rely on occlusive ingredients alone to reduce moisture loss. The PDRN Peptide Cream is built around ingredient synergy. PDRN forms the foundation, while Ceramide NP, EGF (Oligopeptide-1), Ectoin and Beta-Glucan work together to strengthen the skin barrier, maintain hydration and support healthier looking skin over time. The result is a moisturiser designed not only to hydrate, but to actively support the skin's natural resilience and recovery.
The PURESKIN PDRN Peptide Cream combines clinically inspired PDRN, premium EGF peptide and a barrier recovery complex to deliver more than hydration alone.
Clinically inspired polynucleotide technology that supports hydration and healthier looking skin.
Oligopeptide-1 (EGF), a biomimetic peptide selected to support smoother, healthier looking skin.
Ceramide NP, Beta-Glucan and Panthenol help strengthen the skin barrier and lock in moisture.
Ectoin and Sodium Hyaluronate help maintain hydration while protecting against environmental stress.
PDRN SALMON DNA
Most moisturisers focus on hydration. The PURESKIN PDRN Peptide Cream combines three advanced skin technologies: PDRN Technology, Premium EGF Peptide and a Barrier Recovery Complex, to help improve skin comfort, hydration and resilience while supporting healthier looking skin over time.
Hero Technology
Clinically inspired Salmon DNA (PDRN) forms the foundation of the formula, supporting skin hydration and promoting a healthier looking complexion.
Premium EGF Peptide
Powered by Oligopeptide-1 (EGF), a biomimetic peptide selected to support smoother, healthier looking skin and elevate the formula beyond a traditional moisturiser.
Barrier Recovery Complex
Ceramide NP, Beta-Glucan and Panthenol work together to replenish barrier lipids, reinforce the skin's moisture barrier and improve long term skin comfort.
Advanced Hydration Complex
Ectoin and Sodium Hyaluronate provide lasting hydration while helping defend against environmental stress and maintaining skin softness throughout the day.
Your routine
Use morning and night as part of your PDRN ritual. Apply to clean skin and follow with your moisturiser.
☀️Morning
Protect & Hydrate
🌙Evening
Repair & Recover
How it fits together
Cleanse
Daily
Serum
Daily
Cream
Daily
Mask
1–2x weekly
The full routine
Four clinically inspired formulas designed to work together as one complete recovery system.

🫧 Cleanse
PDRN Hydrating Cleanser

🧬 Treat
PDRN Peptide Serum

🛡️ Moisturise
PDRN Peptide Cream

💧 Mask
PDRN Hydrogel Mask (4-pack)
THE PDRN COLLECTION
Discover the complete PURESKIN PDRN Collection. Four clinically inspired formulas developed to cleanse, hydrate, support the skin barrier and promote healthier looking skin.
Shop The PDRN CollectionSecure checkout· Free shipping $120+
Complete the ritual
Free shipping on orders over $120