🧬PDRN (Salmon DNA)
The foundation of the PDRN Collection
A clinically inspired polynucleotide selected to support hydration and healthier looking skin.

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Pairs well with
PDRN Peptide Serum
$71.20 AUD
A hydrating cleanser powered by Salmon DNA (PDRN) and a blend of barrier supporting ingredients to effectively cleanse while leaving the skin feeling fresh and soft.
(7 Reviews)via Judge.mePDRN Skincare
More than a daily cleanse. The PURESKIN PDRN Hydrating Cleanser pairs effective cleansing with advanced hydration and barrier support, combining Salmon DNA (PDRN) with Niacinamide, Panthenol, Ectoin, Ceramide NP, Beta-Glucan and four forms of hyaluronic acid. It lifts away sunscreen, excess oil and daily impurities while supporting the skin's natural moisture barrier, leaving skin feeling clean, hydrated, soft and comfortable.
$47.20 AUD$59.00 AUD
Free shipping on orders over $120 · Same day dispatch before 12pm
Customers who bought this also bought


PDRN Technology
Salmon derived PDRN supports hydration and skin conditioning while cleansing.
Multi Surfactant Cleansing System
A balanced cleansing blend lifts away sunscreen, excess oil and daily impurities for a fresh, thoroughly cleansed finish.
Barrier Support Complex
Panthenol, Beta-Glucan and Ceramide NP help support the skin's natural moisture barrier while you cleanse.
4 Form Hydration System
Hyaluronic acid, Panthenol and Beta-Glucan help replenish hydration for a soft, comfortable after cleansing feel.
Every PURESKIN formula is purposefully developed around clinically inspired actives, barrier first science and ingredient synergy, because healthier looking skin starts with better formulation.
The foundation of the PDRN Collection
A clinically inspired polynucleotide selected to support hydration and healthier looking skin.

Advanced peptide technology
A carefully selected blend of biomimetic peptides that support smoother, firmer looking skin.

Barrier Lipid
Helps replenish essential barrier lipids and strengthen the skin's moisture barrier.

Environmental Defence
An advanced extremolyte that helps defend against environmental stress while maintaining hydration.

Layered Hydration
Multiple molecular weights deliver hydration throughout the skin for immediate and lasting moisture.

Barrier Support
A soothing polysaccharide that helps reinforce the skin barrier while improving moisture retention.

Botanical Recovery
Rich in calming compounds that help comfort stressed skin and support a healthier looking complexion.

Skin Conditioning
A well studied vitamin B3 derivative that supports an even, refined and healthier looking complexion.

PDRN Technology
Multi Surfactant Cleansing System
Barrier Support Complex
Multi Level Hydration
Every formula is designed to complement the next, creating a complete routine focused on hydration, recovery and barrier support.
Simple. Powerful.
Lara Clarke
Verified13/10/2026 · Melbourne, Victoria, Australia
Absolutely love this cleanser! It leaves my skin feeling so soft, hydrated and refreshed without stripping away moisture. It’s super gentle on my skin and perfect for everyday use. Definitely recommend!
Olivia
Verified12/10/2026 · Melbourne, Victoria, Australia
Doesn’t strip my skin at all, really like it
Maya
Verified12/10/2026 · Melbourne, Victoria, Australia
Love this cleanser
Dana
Verified07/10/2026 · Beirut, Beirut, Lebanon
This cleanser is so good! It removes impurities and any leftover makeup while leaving my skin feeling clean, fresh, and hydrated. I’ve really been enjoying it and definitely recommend it! 🤍
Maria Berak
Verified06/10/2026 · Melbourne, Victoria, Australia
This cleanser feels so lux on my skin, perfect for shower face cleansing, absorbs well, removes all the face gunk. Face feels fresh and light.

Jessica
Verified28/10/2026 · Melbourne, Victoria, Australia
I’ve been really impressed with this cleanser! It feels so gentle on my skin but still leaves my face feeling properly clean. It doesn’t leave that tight, dry feeling that I’ve experienced with other cleansers. My skin feels soft, hydrated and refreshed after every use. Definitely one I’ll be repurchasing!

Layla
Verified28/10/2026 · Melbourne, Victoria, Australia
It takes all my makeup off without making my skin feel dry

Click below and leave us a review — it means the world to a small brand like ours.
Leave a reviewFormula Architecture
The PURESKIN PDRN Hydrating Cleanser combines effective daily cleansing with a considered complex of hydrating and skin conditioning ingredients. Powered by Salmon DNA (PDRN) alongside Niacinamide, Panthenol, Ectoin, Ceramide NP and four forms of hyaluronic acid, it removes sunscreen, excess oil and daily impurities while leaving skin feeling clean, refreshed and comfortable, ready for the next step in your routine.
PDRN
The Hero Technology
At the heart of the formula is PDRN (Salmon DNA), paired with a carefully selected blend of hydrating and skin conditioning ingredients.
Hero Ingredient
Cleansing
Multi Surfactant Cleansing System
A multi surfactant system effectively lifts away sunscreen, excess oil and daily impurities for a fresh, thoroughly cleansed finish.
Hero Ingredients
Barrier
Moisture Barrier Support
Panthenol, Ceramide NP and Beta-Glucan provide conditioning and barrier supporting benefits alongside the cleansing system.
Hero Ingredients
Hydration
4 Form Hydration System
Four forms of hyaluronic acid work alongside Ectoin and Niacinamide to support hydration and leave skin feeling soft and comfortable after cleansing.
Hero Ingredients
Many cleansers focus solely on removing surface impurities. The PURESKIN PDRN Hydrating Cleanser takes a more considered approach, combining an effective cleansing system with PDRN, Niacinamide, Panthenol, Ectoin, Ceramide NP, Beta-Glucan and four forms of hyaluronic acid. The result is a cleanser designed to do more than cleanse, leaving skin feeling fresh, comfortable and prepared for the skincare that follows.
Why PURESKIN took a different approach. We believe cleansing should do more than remove the day. By combining PDRN with Niacinamide, Panthenol, Ectoin, Ceramide NP, Beta-Glucan and a four form Hyaluronic Acid complex, we've created a daily cleanser that pairs effective cleansing with hydration and skin conditioning support, preparing the skin for the rest of your routine.
More than removing daily impurities. PDRN, barrier supporting actives and four forms of hyaluronic acid work alongside an effective cleansing system to leave skin feeling clean, hydrated and comfortable.
Salmon derived PDRN supports hydration and skin conditioning while you cleanse.
Effectively removes sunscreen, excess oil and daily impurities for a fresh, thoroughly cleansed finish.
Ceramide NP, Beta-Glucan and Panthenol provide barrier supporting and conditioning benefits alongside cleansing.
Four forms of hyaluronic acid work alongside Ectoin and Niacinamide to support hydration and leave skin feeling soft and comfortable.
PDRN SALMON DNA
Cleansing is the foundation of every skincare routine. That's why we combined PDRN Technology with an effective cleansing system, advanced hydration and a considered complex of barrier supporting ingredients, creating a daily cleanser that removes sunscreen, excess oil and impurities while leaving skin feeling hydrated, comfortable and prepared for the next steps in your routine.
Recovery Technology
Supports hydration and promotes a healthier looking complexion.
Gentle Cleansing
Balanced surfactants remove impurities while helping maintain the skin's natural moisture balance.
Barrier Support
Ceramide NP, Beta-Glucan and Panthenol help reinforce the skin barrier and minimise the feeling of tightness after cleansing.
Hydration
Four forms of hyaluronic acid, Ectoin and Niacinamide replenish moisture while supporting skin comfort.
Your routine
Use morning and night as part of your PDRN ritual. Apply to clean skin and follow with your moisturiser.
☀️Morning
Protect & Hydrate
🌙Evening
Repair & Recover
How it fits together
Cleanse
Daily
Serum
Daily
Cream
Daily
Mask
1–2x weekly
The full routine
Four clinically inspired formulas designed to work together as one complete recovery system.

🫧 Cleanse
PDRN Hydrating Cleanser

🧬 Treat
PDRN Peptide Serum

🛡️ Moisturise
PDRN Peptide Cream

💧 Mask
PDRN Hydrogel Mask (4-pack)
THE PDRN COLLECTION
Discover the complete PURESKIN PDRN Collection. Four clinically inspired formulas developed to cleanse, hydrate, support the skin barrier and promote healthier looking skin.
Shop The PDRN CollectionSecure checkout· Free shipping $120+
Complete the ritual
Free shipping on orders over $120